Hair Loss and Hair Loss Treatment Hair Loss Treatment Peter H. Proctor, PhD, MD Hair Loss Our program for the treatment of hair loss ( " alopecia " ) is the product of 15 years of development and screening of therapeutic agents. We offer both prescription and non-prescription scalp hair regrowth formulations useful for treatment of balding, alopecia, and hair-loss in men and women.   Our Products Proxiphen-N for Hair Loss Treatment Proxiphen-N is a topical formulation of many of the nonprescription hair loss treatment agents coming out of our screening program. These include various SODases, copper-binding peptides, and pyridine-N-oxide hair regrowth stimulators. NANO Shampoo and Conditioner for Hair Loss Treatment NANO shampoo and Conditioner contain the minoxidil-like hair regrowth stimulator NANO ( nicotinic acid N-oxide ). In addition, NANO shampoo contains an SODase-type hair growth stimulating agent. NANO Shampoo is a good adjuvant treatment for either proscription Proxiphen or Proxiphen-N. Proxiphen ( Prescription Formulation for Hair Loss Treatment ) This contains minoxidil, as well as the prescription agents phenytoin and spironolactone ( a potent topically-effective antiandrogen ), plus several other hair-growth stimulating agents It grows significantly more hair on more people than any other agent. Because it contains prescription agents, Proxiphen can only be dispensed on a physician's diagnosis of hair loss. Read the special instructions on how to obtain prescription Proxiphen without coming to Houston. Superoxide dismutases are enzymes which destroy superoxide free radical ( O2- ), an important biological mediator. In many systems ( e.g., blood vessel dialatation, blood clotting, etc.), superoxide opposes the action of another ubiquitous messenger substance, nitric oxide. Nitric oxide is probably haair loss treatment one "natural" form of the hair-growth stimulating drug minoxidil and a natural modulator of hair growth. Apparently, nitric oxide tells hair to start and keep owing, superoxide tells hair to stop growing and fall out. Also, superoxide reacts with nitric oxide to form toxic products. These may be important in mediating parts of the immune response, as well as for tissue damage in a large number of diseases. For example, Superoxide dismutase in its pharmaceutical form " Orgotein " is a potent antiinflammatory agent uner the trade name. In the US, you can only get it if you are a dog or a horse, but it is an approved drug in most of the rest of the world. Because of their effectiveness in the general treatment of inflammatory and degenerative diseases, researchers are constantly looking at SODases and related agents in experimental animal models of disease. In the course of such studies, researchers repeatedly rediscover that SODases stimulate hair growth and decrease hair loss. This discovery is typically followed by a patent application. This is why there are several US and foreign patents on SODases for the treatment of hair loss. BTW, I accidentally discovered this effect of SOD in the late 1970's while doing research on diabetic rats at Bayor College of Medicine. Since I was first, I have the "prime patent". BTW, this patent took over a decade to issue. With some exceptions, the patents listed below cover low molecular weight peptides which complex with copper or other metals to form superoxide dismutases. Again, because